| Shepherd Logistics | Transport |
| Sheraton Grand Doha Resort & Convention Hotel | Leisure and Tourism |
| Sherborne School Qatar | Education |
| Shift Group of Companies | Conglomerates |
| Sidra Agriculture Company W.L.L. | Services |
| Sidra Medical and Research Center | Health Care |
| Siemens W.L.L. | Industrial Manufacturing |
| Signet Qatar WLL | Consumer Goods |
| Silatech | Services |
| Silkland Company | Conglomerates |
| Silver Falcon Contracting & Trading Company W.L.L. | Construction |
| Silverhawk TMA International | Services |
| Simplex Infrastructures Limited - Qatar | Construction |
| Sine Wave Electromechanical Works LLC | Construction |
| Sinmar Marble and Granite | Mining and Metals |
| Sinta Trading & Contracting W.L.L | Conglomerates |
| Sitaf Qatar W.L.L | Telecommunications |
| Site Technology Qatar | Conglomerates |
| Sixty Degrees | Services |
| Sketch Consulting Engineering | Construction |
| SMEC International Pty Ltd | Services |
| SMEET W.L.L. | Industrial Manufacturing |
| Smile Hyper Market | Retail |
| Snow Comms Conceptual Communications & Events | Media |
| Solar Qatar Contracting Company | Construction |
